研究成果

Jornal articles / 発表論文

・From Enantioenriched Donor–Acceptor Cyclopropylcarbinols to Axially Chiral Arylnaphthalenes via Aryldihydronaphthalenes: Central-to-Axial Chirality Exchange
Eur. J. Org. Chem.,:e202101213 2022 [link]
Author:Taichi Saito, Yuka Shimizu, Yusuke Araki, Yoshino Ohgami, Yu Kitazawa, Yoshinori Nishii*

・Asymmetric total synthesis of four bioactive lignans using donor–acceptor cyclopropanes and bioassay of (-)- and (+)-niranthin against hepatitis B and influenza viruses
RSC Advances,12:4635-4639 2022  [link]
Author:Ryotaro Ota, Daichi Karasawa, Mizuki Oshima, Koichi Watashi, Noriko Shimasaki, and Yoshinori Nishii*

・Asymmetric Total Synthesis of a Bioactive Lignanamide Using a 5-endo-tet-type Cyclization of Activated Cyclopropylcarbinols and Synthetic Support for the Reaction Mechanism
Eur. J. Org. Chem.,:e202200563 2022 [link]
Author:Taichi Saito, Kazuki Shibata, Ryohei Takagi, Yuka Shimizu, Naoya Takaki, and Yoshinori Nishii*

・ドナー・アクセプター置換シクロプロパンの環開裂を伴う分子内環化と分子間付加：SN1およびSN2機構を利用する高立体選択的合成
有機合成化学協会誌,76(9):922-937 2018 [link]
Author:西井良典

・An asymmetric total synthesis of tupichilignan A using donor-acceptor cyclopropanes: a structural revision of tupichilignan A
Asian J. Org. Chem.,6:977-980 2017 [link]
Author:Yumi Kimura, Yoshitomo Sone, Taichi Saito, Takehito Mochizuki, and Yoshinori Nishii*

・Catalytic hydrogenolysis of enantioenriched donor-acceptor cyclopropanes using H2 and Palladium on charcoal
Eur. J. Org. Chem.,:2842-2847 2017 [link]
Author:Yoshitomo Sone, Yumi Kimura, Ryotaro Ota, Takehito Mochizuki, Junki Ito and Yoshinori Nishii*

・A formal homo-Nazarov cyclization of enantioenriched donor-acceptor cyclopropanes and following transformations: asymmetric synthesis of multi-substituted dihydronaphthalenes
Org. Biomol. Chem.,15:2443-2449 2017 [link]
Author:Seijiro Takada, Naoya Takaki, Kenta Yamada, and Yoshinori Nishii*

・Stereochemical courses and mechanisms of ring-opening cyclization of donor-acceptor cyclopropylcarbinols and cyclization of 7-benzyloxy dibenzyl lignan lactones
Chem. Lett.,46:524-527 2017 [link]
Author:Takada, seijiro; Sasazawa, Kazuya; Yubune, Toshihide; Takaki, Naoya; Ota, Ryotaro; Nishii, Yoshinori*

・Cu-catalyzed 1,5-addition of Grignard reagents to enantioenriched donor-acceptor cyclopropanes with inversion
Asian J. Org. Chem.,5:1225-1229 2016 [link]
Author:S. Takada, T. Saito, K. Iwata, Y. Nishii*

・Stereoselective oxy-homo-Michael reactions of enantioenriched bicyclic donor–acceptor cyclopropanes to afford optically active trans-α,β-disubstituted γ-butyrolactones possessing three serial chiral centers
Tetrahedron Lett.,57:2422-2425 2016 [link]
Author:Seijiro Takada, Kiitsu Iwata, Toshihide Yubune, and Yoshinori Nishii*

・多置換シクロプロパンの高立体選択的合成と不斉伝搬環拡大反応
有機合成化学協会誌,73(7):701-712 2015 [link]
Author:西井良典

・Highly Stereoselective C-C Bond-Forming Reactions on Cyclopropane Rings using 1-(Methoxycarbonyl)cyclopropylzinc bromides
Chem. Lett.,44:818-820 (open access) 2015 [link]
Author:D. Sakuma, K. Yamada, K. Sasazawa and Y. Nishii*

・First Total Synthesis of (+)-Podophyllic Aldehydes
Chem. Lett.,44:297-299 (open access article) 2015 [link]
Author:Junki Ito, Daichi Sakuma, and Yoshinori Nishii*

・Total Synthesis of (±)-Cyclogalgravin and its Dicarboxyl Analog Using Sc(OTf)3-Mediated Highly Diastereoselective Ring Expansion of 1-(Arylhydroxymethyl)cyclopropanecarboxylates
Chem. Lett.,43:610-611 (open access article) 2014 [link]
Author:Daichi Sakuma, Junki Ito, Ryo Sakai, Ryota Taguchi, Yoshinori Nishii*

・First Total Synthesis of (±)-6′-Methoxyretrojusticidin B Using Regiocontrolled Benzannulation: structural Inconsistency with Procumphthalide A and Its Revisionto 5′-Methoxyretrochinensin
Synlett,15:2275-2278 2010 [link]
Author:Yoshida, E.; Yamashita, D.;Sakai, R.; Tanabe, Y.; and Nishii, Y*.

・Lewis Acid-mediated Highly Regioselective Ring-expansion of Methyl 2-Phenyl-1-(arylhydroxymethyl)cyclopropanecarboxylates
Chem. Lett.,39:194-195 (open access article) 2010 [link]
Author:E. Yoshida, K. Nishida, K. Toriyabe, R.Taguchi, J. Motoyoshiya, Y. Nishii*

・First total synthesis of theopederin B
Tetrahedron Lett.,50:3597-3600 2009 [link]
Author:Y. Nishii, T. Higa, S. Takahashi, T. Nakata

・Toward a Chemiluminescent Molecular Device: Metal Ion-Enhanced Chemiluminescence of Benzylidenacridan with 15-Monoazacrown-5
J. Org. Chem.,74(3):1014-1018 2009 [link]
Author:Motoyoshiya, J.; Tanaka,T.; Kuroe, M.; and Nishii, Y.

・Highly Stereoselective C-Silylation and Alkylation of 1-Chlorocyclopropanecarboxylic Ester Using SmI2
Chem. Lett.,38:1078-1079 2009 [link]
Author:E. Yoshida, T. Nagano, J. Motoyoshiya, Y. Nishii*

・Fluorescence quenching of versatile fluorescent probes based on strongly electron-donating distyrylbenzenes responsive to aromatic chlorinated and nitro compounds, boronic acid and Ca2+
Spectrochimica Acta part A:,69:167-173 2008 [link]
Author:J. Motoyoshiya, Z. Fengqiang, Y. Nishii, H. Aoyama

・SmI2-Promoted Reformatsky-Type Reaction and Acylation of Alkyl 1-Chlorocyclopropancarboxylates
Org. Lett.,10:5453-5456 2008 [link]
Author:T. Nagano, J. Motoyoshiya, A. Kakehi, Y. Nishii*

・Practical, general, and systematic method for optical resolution of gem-dihalo- and monohalo cyclopropanecarboxylic acids utilizing chiral 1,1’-binaphtholmonomethyl ethers: Application to the synthesis of three chiral pesticides
Org. Biomol. Chem.,6:540-547 2008 [link]
Author:H. Yasukochi, T. Atago, A. Tanaka, H. Nakatsuji, E. Yoshida, A. Kakehi, Y. Nishii, Y. Yanabe

・Chemiluminescence of 4-styrylphthalhydrazides with crown etheras ionophore
Luminescence,23:37-41 2008 [link]
Author:J. Motoyoshiya, M. Hotta, Y. Nishii, H. Aoyama

・Synthesis of Hypericin via Emodin Anthrone Derived from a Two-fold Diels-Alder Reaction of 1,4-Benzoquinone
Natural Prod. Commun.,2:67-70 2007 [link]
Author:J. Motoyoshiya, Y. Masue, Y. Nishi, H. Aoyama

・Highly Stereoselective Radical Carbonylations of gem-Dihalocyclopropnane Derivatives with CO
Org. Lett.,9:563-566 2007 [link]
Author:Yoshinori Nishii*, Takao Nagano, Hideki Gotoh, Ryohei Nagase, Jiro Motoyoshiya, Hiromu Aoyama, Yoo Tanabe*

・Synthesis of Unsymmetrically and Highly Substituted Thiophenes Utilizing Regioselective Ring-expansion of gem-Dichlorocyclopropyl Ketones with Lawesson’s Reagent
Chem. Lett.,36(1):62-63 2007 [link]
Author:Takao Nagano, Hiroki Kimoto, Hidefumi Nakatsuji, Jiro Motoyoshiya, Hiromu Aoyama, Yoo Tanabe,* Yoshinori Nishii*

・Regiocontrolled benzannulation of diaryl (gem-dichlorocyclopropyl)methanols for the synthesis of unsymmetrically substituted alpha-arylnaphthalenes: Application to total synthesis of natural lignan lactones
JOURNAL OF ORGANIC CHEMISTRY,70(7):2667-2678 2005 [link]
Author:Nishii, Y; Yoshida, T; Asano, H; Wakasugi, K; Morita, J; Aso, Y; Yoshida, E; Motoyoshiya, J; Aoyama, H; Tanabe, Y

・Poly(benzyl ether) dendrimers with strongly fluorescent distyrylbenzene cores as the fluorophores for peroxyoxalate chemiluminescence: insulating effect of dendritic structures on fluorescent sites
TETRAHEDRON,61(46):11020-11026 2005 [link]
Author:Koike, R; Katayose, Y; Ohta, A; Motoyoshiya, J; Nishii, Y; Aoyama, H

・中心不斉から軸不斉への転写と変換
化学と工業,57:1212 2004(Nov.) [link]
Author:西井良典

・Chemiluminescent Autoxidation of alpha-Silyl Carbanios Derived From 9-Silyl-10-Methylacridanes
Heterocycles,:1667-1672 2004 [link]
Author:Jiro Motoyoshiya, Kunihiko Tokutake, Motoki Kuroe, Sachiko Yoshioka, Yoshinori Nishii, and Hiromu Aoyama

・A Facile Synthesis of the Angucyclinone Antibiotic (+)-Rubiginone B2 Involving the BF3-Mediated Diels-Alder Reaction of Juglone
Synthesis,:2099-2102 2004 [link]
Author:Jiro Motoyoshiya, Yusuke Masue, Gento Iwayama, Sachiko Yoshioka, Yoshinori Nishii, and Hiromu Aoyama

・Chirality Exchange from sp3 Central Chirality to Axial Chirality: Benzannulation of Optically Active Diaryl-2,2-dichlorocyclopropylmethanols to Axially Chiral alpha-Arylnaphthalenes
J. Am. Chem. Soc.,126:5358-5359 2004 [link]
Author:Yoshinori Nishii, Kazunori Wakasugi, Keisuke Koga, Yoo Tanabe

・Reactions of 9-Phosphorylacridines with Aqueous Hydrogen Peroxide Accompained by Weak Chemiluminescence: Remarkable Substituent Effect on Emission Efficiency
Heterocycles,60:2543-2549 2003 [link]
Author:Jiro Motoyoshiya, Rie Shima, Yutaka Takaguchi, Yoshinori Nishii, and Hiromu Aoyama

・Total synthesis of pederin, an insect toxin: an efficient synthesis of the right half, (+)-benzoylpedamide
Tetrahedron (Symposium-in-print),58:6359 2002 [link]
Author:T. Takemura, Y. Nishii, S Takahasi, J. Kobayashi, and T. Nakata

・Does the Facile Reductive Rearrangement of 2-Allyloxycyclohexenone with Bu3SnH Occur by a Radical-Accelerated Claisen Rearrangement or an Stannyloxy-Accelerated Claisen Rearrangement?
J. Am. Chem. Soc.,121:8955-8956 1999 [link]
Author:D. P. Curran and Y. Nishii